Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | FDPS | P14324 | 6/20 | 0.59 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516269 | 0.80 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL14980355 | 0.77 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL26628880 | 0.77 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL11240731 | 0.77 | FDPS (0.59) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL11559809 | 0.76 | FDPS (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL11806774 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL74145 | 0.75 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL11231844 | 0.75 | FDPS (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL31358573 | 0.75 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL29582746 | 0.75 | FDPS (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160729-A1 | COMPOSITION AND METHOD FOR TREATING CANCER | CELLWORKS RESEARCH INDIA PVT. LTD (IN) | 2014-10-02 | — | — | WO | disclosed |
| US-20140274967-A1 | Polyisoprenyl derivatives and uses thereof | COYOTE PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | US | disclosed |
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | TARGANTA THERAPEUTICA INC. (CA) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | BPGM, PSPH, PGLS | CYP1A2 3850/4885CYP3A4 2952/4885CYP2C9 2368/4885 |
| US-20140274967-A1 | Polyisoprenyl derivatives and uses thereof | PHOSPHO1, GGPS1, PPIP5K2 | CYP1A2 2079/4885CYP3A4 875/4885CYP2C9 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.