Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238134 | 0.92 | MEN1 (0.59) | CYP19A1TBXAS1MEN1KMT2AATM | |
| SCHEMBL11240927 | 0.88 | CYP19A1 (0.58) | CYP19A1TBXAS1MEN1KMT2AATM | |
| SCHEMBL11241508 | 0.86 | CYP19A1 (0.66) | CYP19A1TBXAS1ALDH1A1TSHRMAPT | |
| SCHEMBL11249784 | 0.85 | TBXAS1 (0.65) | CYP19A1TBXAS1ALDH1A1GAAKDM4E | |
| SCHEMBL11236509 | 0.85 | ALDH1A1 (0.55) | CYP19A1TBXAS1ALDH1A1MAPTKDM4E | |
| SCHEMBL11259784 | 0.85 | TBXAS1 (0.55) | TBXAS1ALDH1A1KDM4EQPCT | |
| SCHEMBL11236348 | 0.85 | CYP19A1 (0.56) | CYP19A1TBXAS1ALDH1A1QPCTCYP11B1 | |
| SCHEMBL11260419 | 0.83 | TBXAS1 (0.59) | TBXAS1 | |
| SCHEMBL11242023 | 0.83 | KMT2A (0.53) | TBXAS1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11233236 | 0.82 | HMOX1 (0.57) | CYP19A1TBXAS1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |