Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446434 | 0.86 | RAPGEF4 (0.50) | CYP1A2CYP2D6FERMT2LMNAGAA | |
| SCHEMBL11235154 | 0.77 | TAAR1 (0.46) | CYP1A2CYP2D6LMNAALDH1A1TDP1 | |
| SCHEMBL7560933 | 0.77 | TDP1 (0.45) | LMNAGAAALDH1A1RAPGEF4TDP1 | |
| Hydrochloric Acid SCHEMBL28300035 | 0.77 | MRGPRX4 (0.35) | LMNAGAAALDH1A1TDP1CYP3A4 | |
| SCHEMBL19986641 | 0.76 | STK17A (0.37) | CYP1A2CYP2D6FERMT2LMNAGAA | |
| SCHEMBL14446421 | 0.74 | TSHR (0.47) | LMNAALDH1A1RAPGEF4TSHRMEN1 | |
| SCHEMBL11238762 | 0.72 | FERMT2 (0.53) | CYP1A2CYP2D6FERMT2LMNAGAA | |
| SCHEMBL11437491 | 0.71 | RAPGEF4 (0.42) | LMNAGAAALDH1A1RAPGEF4TDP1 | |
| SCHEMBL9164991 | 0.71 | LMNA (0.44) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL11226781 | 0.71 | SIGMAR1 (0.43) | CYP1A2CYP2D6LMNASIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |