Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.60 |
| ▸ | RXRB | P28702 | 6/20 | 0.60 |
| ▸ | RXRG | P48443 | 5/20 | 0.60 |
| ▸ | CYP26B1 | Q9NR63 | 8/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | RARG | P13631 | 3/20 | 0.51 |
| ▸ | RARA | P10276 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245625 | 0.89 | RXRA (0.49) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL6148042 | 0.88 | CYP26A1 (0.71) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL8839031 | 0.86 | RXRA (0.57) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL8102850 | 0.83 | RXRA (0.55) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL2095481 | 0.79 | RXRA (0.57) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL23092045 | 0.78 | PPARG (0.71) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL29605538 | 0.78 | CYP26B1 (0.83) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL21776768 | 0.78 | CYP26B1 (0.83) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| SCHEMBL8102425 | 0.78 | ALDH1A1 (0.58) | RXRARXRBRXRGCYP26B1CYP26A1 | |
| Zinc Ion SCHEMBL9587456 | 0.78 | RXRA (0.49) | RXRARXRBRXRGCYP26B1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | disclosed |