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Zinc Ion

Zinc Ion

SCHEMBL9587456

CC(C(=O)[O-])C(=O)Cc1ccc2c(c1)C(C)(C)CCC2(C)C.CC(C(=O)[O-])C(=O)Cc1ccc2c(c1)C(C)(C)CCC2(C)C.[Zn+2]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 7/20 0.49
▸ RXRB P28702 4/20 0.49
▸ RXRG P48443 3/20 0.49
▸ CYP26B1 Q9NR63 8/20 0.47
▸ CYP26A1 O43174 7/20 0.47
▸ PPARG P37231 3/20 0.43
▸ RARA P10276 2/20 0.43
▸ RARB P10826 2/20 0.43
▸ RARG P13631 2/20 0.43
▸ CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11241526 0.78 RXRA (0.60) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL8839031 0.75 RXRA (0.57) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL8102850 0.73 RXRA (0.55) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL23092045 0.71 PPARG (0.71) RXRARXRBRXRGCYP26B1CYP26A1
Zinc Ion SCHEMBL9724367 0.70 CYP3A4 (0.51) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL2095481 0.69 RXRA (0.57) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL11245625 0.68 RXRA (0.49) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL21776768 0.68 CYP26B1 (0.83) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL8102425 0.68 ALDH1A1 (0.58) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL9586713 0.68 CYP3A4 (0.51) RXRARXRBRXRGCYP26B1CYP26A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5194663-A Antilipemic agents for skins SOCIETE ANONYME DITE: L'OREAL (FR) 1993-03-16 — — US disclosed