Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243304 | 0.80 | LMNA (0.37) | ALDH1A1TDP1HPGDTSHRRECQL | |
| SCHEMBL10991133 | 0.73 | BRD4 (0.38) | POLBALDH1A1HPGDCYP2D6 | |
| SCHEMBL13715066 | 0.71 | ARG1 (0.34) | — | |
| SCHEMBL8016763 | 0.71 | ARG1 (0.34) | — | |
| SCHEMBL23884534 | 0.70 | AKR1C1 (0.37) | ALDH1A1TDP1NPSR1CYP2D6TSHR | |
| SCHEMBL1818488 | 0.70 | AKR1C1 (0.37) | ALDH1A1TDP1NPSR1CYP2D6TSHR | |
| SCHEMBL28507597 | 0.69 | LMNA (0.36) | ALDH1A1TDP1HPGDTSHR | |
| SCHEMBL10987532 | 0.68 | LMNA (0.36) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL11237656 | 0.68 | LMNA (0.36) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL10992272 | 0.68 | LMNA (0.37) | KMT2APOLBL3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316905-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |