Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360916 | 0.84 | APP (0.42) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL11276032 | 0.82 | CYP3A4 (0.42) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL8496952 | 0.80 | CYP3A4 (0.51) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL5529539 | 0.79 | PPARA (0.50) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL11003522 | 0.76 | PPARA (0.42) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL11268638 | 0.76 | PPARA (0.50) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL10827183 | 0.76 | PPARA (0.58) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL11546404 | 0.76 | CYP3A4 (0.48) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL1148152 | 0.76 | NPSR1 (0.45) | PPARACYP3A4CYP1A2KMT2ACYP2C19 | |
| SCHEMBL5532010 | 0.75 | PPARG (0.54) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348534-A | Preparation of 2-aryloxy-2-haloproptonic acid compounds | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |