Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239064 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11230933 | 0.83 | MEN1 (0.35) | ALDH1A1HPGDHSD17B10TDP1KMT2A | |
| SCHEMBL11248927 | 0.83 | ALDH1A1 (0.39) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11370697 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11374917 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11441974 | 0.80 | TDP1 (0.48) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11377272 | 0.80 | TDP1 (0.48) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11448925 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11375868 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HPGDCYP3A4HIF1AHSD17B10 | |
| SCHEMBL11367710 | 0.76 | MAPT (0.42) | ALDH1A1HPGDKMT2AMEN1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |