Dibromsalan

Dibromsalan

SCHEMBL646973

O=C(Nc1ccc(Br)cc1)c1cc(Br)ccc1O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.73
F2 P00734 1/20 0.73
F10 P00742 1/20 0.73
PLAT P00750 1/20 0.73
ALOX15 P16050 2/20 0.71
TMPRSS4 Q9NRS4 1/20 0.66
MAPT P10636 4/20 0.66
CYP1A2 P05177 3/20 0.66
CYP2C9 P11712 2/20 0.66
ALDH1A1 P00352 2/20 0.66
MEN1 O00255 1/20 0.66
EGFR P00533 1/20 0.66
LMNA P02545 1/20 0.66
ERBB2 P04626 1/20 0.66
LCK P06239 1/20 0.66
PTGS1 P23219 1/20 0.66
MAPK1 P28482 1/20 0.66
HTT P42858 1/20 0.66
KMT2A Q03164 1/20 0.66
MAPK14 Q16539 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibromsalan SCHEMBL29496335 1.00 PLAU (0.73) PLAUF2F10PLATALOX15
Dibromsalan SCHEMBL29211119 0.94 PLAU (0.66) PLAUF2F10PLATALOX15
Bromochlorosalicylanilide SCHEMBL152257 0.90 P2RX1 (0.77) PLAUF2F10PLATALOX15
SCHEMBL330113 0.90 TMPRSS4 (0.67) PLAUF2F10PLATALOX15
SCHEMBL19024613 0.90 PLAU (0.61) PLAUF2F10PLATALOX15
SCHEMBL30343477 0.90 TMPRSS4 (0.67) PLAUF2F10PLATALOX15
Tribromsalan SCHEMBL11242287 0.89 MAPT (0.86) PLAUF2F10PLATALOX15
SCHEMBL1628928 0.87 PLAU (0.62) PLAUF2F10PLATALOX15
SCHEMBL11683279 0.87 P2RX1 (0.82) TMPRSS4ALDH1A1MEN1LMNAKMT2A
SCHEMBL11683814 0.87 PLAU (0.58) PLAUF2F10PLATALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 755 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091043-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS DATA2DISCOVERY INC (US) 2026-04-02 US claimed
WO-2024064209-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS DATA2DISCOVERY, INC. (US) 2024-03-28 WO claimed
US-20230323279-A1 MUTANT ALGAE, METHOD OF PREPARATION AND APPLICATION THEREOF RELIANCE INDUSTRIES LIMITED (IN) 2023-10-12 US claimed
US-20220000813-A1 Therapeutic Agent For Phosphodiesterase Inhibition And Its Related Disorders NOVALEAD PHARMA INC (US) 2022-01-06 US claimed
EP-3927334-A1 NONHORMONAL UNISEX CONTRACEPTIVES The Regents of The University of California (US) 2021-12-29 EP claimed
US-20210369652-A1 Nonhormonal Unisex Contraceptives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-12-02 US claimed
US-11147779-B2 Therapeutic agent for phosphodiesterase inhibition and its related disorders Deshpande, Supreet K. (US) 2021-10-19 US claimed
CN-107809908-B Aqueous antimicrobial film-forming composition for teat treatment by spray application 艺康美国股份有限公司 2021-04-13 CN claimed
EP-3263145-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2021-01-20 EP claimed
US-20200038350-A1 CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE DUKE UNIVERSITY 2020-02-06 US claimed
WO-1999007382-A1 MACROPHAGE SCAVENGER RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF CARDIOVASCULAR DISEASES SMITHKLINE BEECHAM CORPORATION (US) 1999-02-18 WO claimed
EP-0710105-A4 SYNERGISTIC ANTHELMINTIC COMPOSITIONS UNIV AUSTRALIAN (AU) 1998-06-10 EP claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
EP-0710105-A1 SYNERGISTIC ANTHELMINTIC COMPOSITIONS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1996-05-08 EP claimed
WO-1994028887-A1 SYNERGISTIC ANTHELMINTIC COMPOSITIONS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1994-12-22 WO claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
US-4323466-A Germicide LEVER BROTHERS COMPANY (US) 1982-04-06 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4173632-A Fasciolicidal compositions E. R. SQUIBB & SONS, INC. (US) 1979-11-06 US claimed
US-3956510-A NESTING, CYLINDERS, LOOPS BEALL NELSON J 1976-05-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11147779-B2 Therapeutic agent for phosphodiesterase inhibition and its related disorders PDE9A, PDE3A, PDE12 PLAU 1479/4885F2 1247/4885F10 1903/4885
US-20260091043-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS AHCY, MACO1, ME3 PLAU 1914/4885F2 4310/4885F10 3869/4885
US-20200038350-A1 CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE SFRP1, FZD7, WNT1 PLAU 2354/4885F2 2158/4885F10 3597/4885
US-20210369652-A1 Nonhormonal Unisex Contraceptives UQCRC1, UQCRC2, MCU PLAU 4201/4885F2 1074/4885F10 981/4885
US-20230323279-A1 MUTANT ALGAE, METHOD OF PREPARATION AND APPLICATION THEREOF STOM, PPA1, ALAD PLAU 4630/4885F2 4616/4885F10 4209/4885
US-20220000813-A1 Therapeutic Agent For Phosphodiesterase Inhibition And Its Related Disorders PDE3A, PDE9A, PDE12 PLAU 1446/4885F2 1258/4885F10 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.