Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263574 | 0.88 | DHODH (0.32) | DHODHRXFP1 | |
| SCHEMBL11251007 | 0.86 | SOS1 (0.40) | SOS1LMNANOTUMRXFP1KDM4E | |
| SCHEMBL11248479 | 0.86 | SOS1 (0.36) | SOS1LMNANOTUMRXFP1KDM4E | |
| SCHEMBL11253445 | 0.85 | TDP1 (0.37) | SOS1LMNANOTUMRXFP1KDM4E | |
| SCHEMBL11246024 | 0.84 | PDE3B (0.33) | PDE3BPDE3AP2RX3 | |
| SCHEMBL11252299 | 0.83 | XDH (0.33) | PDE3BPDE3AP2RX3 | |
| SCHEMBL11240936 | 0.83 | SOS1 (0.40) | SOS1LMNANOTUMRXFP1KDM4E | |
| SCHEMBL11260601 | 0.82 | SOS1 (0.41) | SOS1LMNANOTUMRXFP1KDM4E | |
| SCHEMBL11252931 | 0.82 | TRPA1 (0.36) | PDE3BPDE3AP2RX3 | |
| SCHEMBL11251640 | 0.81 | SOS1 (0.37) | SOS1LMNANOTUMRXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |