Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252299 | 0.91 | XDH (0.33) | PDE3BPDE3AP2RX3TRPA1PDE5A | |
| SCHEMBL11252931 | 0.90 | TRPA1 (0.36) | PDE3BPDE3AP2RX3TRPA1PDE5A | |
| SCHEMBL11243215 | 0.88 | TRPA1 (0.33) | PDE3BPDE3ATRPA1 | |
| SCHEMBL11252271 | 0.88 | POLB (0.36) | PDE3BPDE3ATRPA1 | |
| SCHEMBL11250185 | 0.88 | PDE3B (0.31) | PDE3BPDE3ATRPA1 | |
| SCHEMBL11248725 | 0.87 | PDE3B (0.33) | PDE3BPDE3ATRPA1 | |
| SCHEMBL11244450 | 0.86 | PTGS1 (0.33) | PDE3BPDE3APDE5A | |
| SCHEMBL11246911 | 0.85 | HTR2A (0.31) | — | |
| SCHEMBL11263574 | 0.85 | DHODH (0.32) | — | |
| SCHEMBL11242427 | 0.84 | SOS1 (0.35) | PDE3BPDE3AP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |