Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235019 | 0.82 | SIGMAR1 (0.43) | ADRB2MTNR1AHPGDHTTCTNNB1 | |
| SCHEMBL4100261 | 0.70 | MTNR1A (0.58) | MTNR1AHPGDHTTMAPK1 | |
| SCHEMBL30496750 | 0.70 | MTNR1A (0.58) | MTNR1AHPGDHTTMAPK1 | |
| Hydrochloric Acid SCHEMBL28128851 | 0.69 | MTNR1A (0.57) | MTNR1AHPGDHTTMAPK1 | |
| SCHEMBL11238592 | 0.67 | CTNNB1 (0.50) | ADRB2HPGDHTTCTNNB1SIGMAR1 | |
| SCHEMBL8438060 | 0.67 | ADRB2 (0.56) | ADRB2DNM1CTNNB1SIGMAR1ADRB1 | |
| SCHEMBL7402726 | 0.66 | CTNNB1 (0.53) | ADRB2MTNR1AHPGDHTTCTNNB1 | |
| SCHEMBL8685913 | 0.66 | HPGD (0.45) | ADRB2MTNR1AHPGDHTTCTNNB1 | |
| SCHEMBL11410876 | 0.65 | CTNNB1 (0.55) | MTNR1AHPGDHTTCTNNB1CYP1A2 | |
| SCHEMBL7394253 | 0.65 | CTNNB1 (0.54) | ADRB2HPGDHTTCTNNB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317832-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AGENTS | KLINGLER KARL HEINZ | 1982-03-02 | — | — | US | disclosed |