Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.37 |
| ▸ | HTR3B | O95264 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | GPX4 | P36969 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057637 | 0.76 | ABL1 (0.74) | ABL1ALDH1A1MEN1KMT2A | |
| SCHEMBL10656731 | 0.76 | ABL1 (0.66) | ABL1ALDH1A1MEN1ALOX15TSHR | |
| SCHEMBL11191902 | 0.74 | ABL1 (0.56) | ABL1ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL10846355 | 0.74 | HTR3E (0.44) | ALOX5ALDH1A1GRM4HTR3EHTR3B | |
| SCHEMBL25138507 | 0.73 | ABL1 (1.00) | ABL1 | |
| SCHEMBL25703688 | 0.73 | ABL1 (1.00) | ABL1 | |
| SCHEMBL10656600 | 0.70 | ABL1 (0.58) | ABL1ALDH1A1MEN1ALOX15TSHR | |
| SCHEMBL10916309 | 0.70 | ABL1 (0.61) | ABL1ALOX5ALDH1A1KMT2A | |
| SCHEMBL11185863 | 0.68 | ABL1 (0.44) | ABL1ALOX5ALDH1A1GRM4HTR3E | |
| SCHEMBL7393570 | 0.67 | HTR3E (0.44) | ALOX5ALDH1A1GRM4HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347251-A | ANTIINFLAMMATORY, ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-08-31 | — | — | US | claimed |
| US-4347251-A | ANTIINFLAMMATORY, ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-08-31 | — | — | US | disclosed |