Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242489 | 1.00 | AR (0.51) | ARCYP19A1NR3C2CYP17A1LMNA | |
| SCHEMBL11234814 | 0.85 | AR (0.65) | ARCYP19A1NR3C2CYP17A1LMNA | |
| SCHEMBL11239927 | 0.85 | AR (0.68) | ARCYP19A1NR3C2CYP17A1LMNA | |
| SCHEMBL11239910 | 0.85 | AR (0.68) | ARCYP19A1NR3C2CYP17A1LMNA | |
| SCHEMBL11245421 | 0.77 | CYP17A1 (0.61) | ARCYP19A1NR3C2CYP17A1LMNA | |
| SCHEMBL11245428 | 0.77 | CYP17A1 (0.61) | ARCYP19A1NR3C2CYP17A1LMNA | |
| SCHEMBL9622429 | 0.77 | LMNA (0.67) | ARNR3C2CYP17A1LMNACYP3A4 | |
| SCHEMBL13941337 | 0.77 | LMNA (0.67) | ARNR3C2CYP17A1LMNACYP3A4 | |
| SCHEMBL853001 | 0.77 | LMNA (0.67) | ARNR3C2CYP17A1LMNACYP3A4 | |
| SCHEMBL9128571 | 0.77 | SHBG (0.65) | ARCYP19A1CYP17A1LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |