Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 4/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | PGR | P06401 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128581 | 1.00 | SHBG (0.65) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL13965592 | 0.86 | LMNA (0.67) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL572198 | 0.86 | LMNA (0.67) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL11240496 | 0.85 | LMNA (0.68) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL11240498 | 0.85 | LMNA (0.68) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL295690 | 0.85 | LMNA (0.51) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL6693993 | 0.84 | LMNA (0.53) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL6693991 | 0.84 | LMNA (0.53) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| Benorterone SCHEMBL635671 | 0.84 | SHBG (0.81) | SHBGNR3C1ALDH1A1PGRHTR2B | |
| SCHEMBL11647496 | 0.83 | CYP17A1 (0.48) | SHBGNR3C1ALDH1A1PGRHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389624-A | Antiandrogenic [3,2-c]pyrazole and [3,2-d]triazole steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5236912-A | Treating prostate hyperplasia and carcinoma | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
| EP-0538312-A1 | Anti-androgenic [3,2-d]triazole steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000992-A1 | ANTI-ANDROGENIC [3,2-c]PYRAZOLE AND [3,2-d]TRIAZOLE STEROIDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1992-01-23 | — | — | WO | disclosed |
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |