Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547501 | 0.94 | CYP1A2 (0.51) | SLC6A2SLC6A4SLC6A3OPRL1ALDH1A1 | |
| Iodide SCHEMBL11547732 | 0.93 | CYP1A2 (0.50) | SLC6A2SLC6A4SLC6A3OPRL1ALDH1A1 | |
| SCHEMBL11260608 | 0.86 | OPRM1 (0.50) | OPRM1OPRD1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL11242548 | 0.86 | SLC6A4 (0.60) | OPRM1OPRD1OPRK1SLC6A2SLC6A4 | |
| Bromide SCHEMBL11248173 | 0.85 | OPRM1 (0.49) | OPRM1OPRD1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL11542030 | 0.85 | CXCR3 (0.57) | OPRL1POLBCXCR3SIGMAR1 | |
| SCHEMBL11542033 | 0.85 | CXCR3 (0.57) | OPRL1POLBCXCR3SIGMAR1 | |
| SCHEMBL11257297 | 0.84 | SLC6A4 (0.54) | OPRM1OPRD1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL17815774 | 0.84 | OPRL1 (0.53) | OPRM1OPRL1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16385999 | 0.84 | OPRL1 (0.53) | OPRM1OPRL1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |