Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22486710 | 0.90 | ADRB1 (0.74) | HTTADRB1CYP2D6LMNAMEN1 | |
| SCHEMBL11246808 | 0.89 | CYP2D6 (0.65) | HTTADRB1CYP2D6LMNAMEN1 | |
| SCHEMBL11143700 | 0.88 | HTT (0.50) | HTTADRB1CYP2D6LMNAMEN1 | |
| Cicloprolol SCHEMBL9681296 | 0.84 | ADRB1 (0.80) | ADRB1CYP2D6LMNAMEN1CYP1A2 | |
| Cicloprolol SCHEMBL9680771 | 0.84 | ADRB1 (0.80) | ADRB1CYP2D6LMNAMEN1CYP1A2 | |
| Cicloprolol SCHEMBL634972 | 0.84 | ADRB1 (0.80) | ADRB1CYP2D6LMNAMEN1CYP1A2 | |
| Cicloprolol SCHEMBL613271 | 0.83 | LMNA (0.81) | ADRB1CYP2D6LMNAMEN1CYP1A2 | |
| Cicloprolol SCHEMBL22734881 | 0.83 | LMNA (0.81) | ADRB1CYP2D6LMNAMEN1CYP1A2 | |
| Cicloprolol SCHEMBL613272 | 0.82 | ADRB1 (0.77) | ADRB1CYP2D6LMNAMEN1CYP1A2 | |
| SCHEMBL3457917 | 0.81 | ADRB1 (0.71) | ADRB1CYP2D6LMNAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311708-A | ADRENERGIC BLOCKING AGENTS | SYNTHELABO (FR) | 1982-01-19 | — | — | US | claimed |
| US-4311708-A | ADRENERGIC BLOCKING AGENTS | SYNTHELABO (FR) | 1982-01-19 | — | — | US | disclosed |
| US-4252984-A | 1-/P-/2-/CYCLOPROPYLMETHOXY/ETHYL/PHENOXY/-3-ISOPROPYLAMINO-2 -PROPANOL | SYNTHELABO (FR) | 1981-02-24 | — | — | US | disclosed |