Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cicloprolol SCHEMBL9680771 | 1.00 | ADRB1 (0.80) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Cicloprolol SCHEMBL634972 | 1.00 | ADRB1 (0.80) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Cicloprolol SCHEMBL613271 | 0.99 | LMNA (0.81) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Cicloprolol SCHEMBL22734881 | 0.99 | LMNA (0.81) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Cicloprolol SCHEMBL613272 | 0.98 | ADRB1 (0.77) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| SCHEMBL11247586 | 0.96 | ADRB1 (0.75) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Betaxolol SCHEMBL23531 | 0.89 | ADRB1 (1.00) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Betaxolol SCHEMBL4997902 | 0.89 | ADRB1 (1.00) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Levobetaxolol SCHEMBL23532 | 0.89 | ADRB1 (1.00) | ADRB1LMNAMEN1KMT2ACYP2D6 | |
| Betaxolol SCHEMBL6512495 | 0.89 | ADRB1 (1.00) | ADRB1LMNAMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498705-A1 | Phenol ethers derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1992-08-12 | — | — | EP | claimed |
| EP-0498705-A1 | Phenol ethers derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1992-08-12 | — | — | EP | disclosed |