SCHEMBL126192

SCHEMBL126192

COc1ccc2c(c1)C(=O)CC(c1ccccc1)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 1.00
ABCG2 Q9UNQ0 3/20 1.00
ABCB1 P08183 1/20 1.00
MAOB P27338 10/20 0.80
CYP19A1 P11511 6/20 0.80
NPC1 O15118 2/20 0.73
MAPT P10636 2/20 0.73
RAB9A P51151 2/20 0.73
KDM4E B2RXH2 3/20 0.71
HSD17B10 Q99714 3/20 0.71
ALDH1A1 P00352 2/20 0.71
MAPK1 P28482 2/20 0.71
GAA P10253 1/20 0.71
ALOX15 P16050 1/20 0.71
TSHR P16473 1/20 0.71
CYP3A4 P08684 2/20 0.69
STS P08842 1/20 0.69
HPGD P15428 1/20 0.63
ADORA3 P0DMS8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4394832 1.00 AR (1.00) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL22680315 0.93 ABCB1 (0.87) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL29020378 0.90 ABCB1 (0.82) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL30499387 0.90 ABCB1 (0.82) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL12067063 0.89 ABCB1 (0.81) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL1895399 0.89 MAOB (1.00) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL131515 0.89 MAOB (1.00) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL30777574 0.88 MAOB (0.81) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL18893710 0.88 MAOB (0.81) ARABCG2ABCB1MAOBCYP19A1
SCHEMBL1823145 0.86 AR (0.76) ARABCG2ABCB1MAOBCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130959-A1 FUNGAL EXTRACTS AND FLAVOR COMBINATIONS THEREOF Mycotechnology, Inc. (US) 2026-05-14 US claimed
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO claimed
WO-2024242892-A2 MATERIALS AND METHODS FOR MASKING BITTERNESS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-11-28 WO claimed
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2023-06-08 US claimed
EP-4146194-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS Gretals Australia Pty Ltd (AU) 2023-03-15 EP claimed
US-20220193162-A1 FUNGAL EXTRACTS AND FLAVOR COMBINATIONS THEREOF Mycotechnology, Inc. (US) 2022-06-23 US claimed
EP-3955946-A1 FUNGAL EXTRACTS AND FLAVOR COMBINATIONS THEREOF Mycotechnology, Inc. (US) 2022-02-23 EP claimed
WO-2021222987-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2021-11-11 WO claimed
WO-2020214801-A1 FUNGAL EXTRACTS AND FLAVOR COMBINATIONS THEREOF Mycotechnology, Inc. (US) 2020-10-22 WO claimed
CN-109890376-A Composition is used in PGC-1 α activation 三得利控股株式会社 2019-06-14 CN claimed
EP-0004579-B1 FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1982-08-18 EP claimed
US-20260033492-A1 Pest Repellents and Uses Thereof SENSORYGEN INC (US) 2026-02-05 US disclosed
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO disclosed
US-12280129-B2 Compositions and methods for improved skin care PINSKY MARK A (US) 2025-04-22 US disclosed
CN-118649665-B Preparation method of vacuum gas-phase derived chiral separation material 宁波大学 2025-02-07 CN disclosed
US-6051602-A METHODS FOR PREVENTION OR TREATING SKIN DISORDERS USING FLAVONOID COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2000-04-18 US disclosed
WO-1999047118-A1 COMPOSITIONS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
WO-1999047113-A1 COMPOSITIONS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
WO-1999047119-A1 METHODS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
WO-1998052935-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 1998-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033492-A1 Pest Repellents and Uses Thereof F3, TFPI, FLI1 AR 4093/4885ABCG2 4389/4885ABCB1 2541/4885
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS MMP1, COL1A1, SERPINB1 AR 3364/4885ABCG2 4063/4885ABCB1 2698/4885
US-20260130959-A1 FUNGAL EXTRACTS AND FLAVOR COMBINATIONS THEREOF TAS2R8, TAS2R40, TAS1R3 AR 1929/4885ABCG2 1230/4885ABCB1 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.