Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536112 | 0.88 | HRH4 (0.36) | MAOBCYP19A1PGRARMEN1 | |
| SCHEMBL7195895 | 0.87 | ALDH1A1 (0.50) | LMNAMAOBCYP19A1CYP3A4GABRA1 | |
| SCHEMBL6700954 | 0.82 | CYP19A1 (0.45) | MAOBCYP19A1PGRNPC1RAB9A | |
| SCHEMBL18893709 | 0.82 | MAOB (0.53) | LMNAMAOBCYP19A1CYP3A4GABRA1 | |
| SCHEMBL126193 | 0.82 | ABCG2 (0.55) | LMNAMAOBCYP19A1CYP3A4GABRA1 | |
| SCHEMBL127705 | 0.81 | MAPT (0.52) | LMNAMAOBCYP19A1CYP3A4GABRA1 | |
| SCHEMBL27543000 | 0.79 | ESR2 (0.44) | MAOBCYP19A1CYP3A4ARMEN1 | |
| SCHEMBL7030025 | 0.79 | LMNA (0.48) | LMNAMAOBCYP19A1CYP3A4GABRA1 | |
| SCHEMBL29020379 | 0.78 | ALDH1A1 (0.49) | LMNAMAOBCYP19A1CYP3A4GABRA1 | |
| SCHEMBL28710319 | 0.74 | CYP19A1 (0.53) | LMNAMAOBCYP19A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | claimed |