Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034901 | 0.81 | ELANE (0.31) | ELANE | |
| SCHEMBL5652000 | 0.79 | KMT2A (0.43) | KMT2ANPSR1RAB9ALMNANPC1 | |
| SCHEMBL278457 | 0.78 | — | — | |
| SCHEMBL10751495 | 0.77 | NOS1 (0.32) | KMT2ALMNATSHRELANEPDE4B | |
| SCHEMBL128494 | 0.75 | — | — | |
| SCHEMBL2853189 | 0.74 | — | — | |
| SCHEMBL440250 | 0.74 | — | — | |
| SCHEMBL28346497 | 0.73 | KDM4E (0.31) | ELANEPDE4B | |
| SCHEMBL601253 | 0.73 | FDPS (0.33) | KMT2AHPGDLMNATSHRELANE | |
| SCHEMBL7901150 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017066-B1 | N,N-DIMETHYL-O-PYRAZOLYL ESTERS OF CARBAMIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1982-04-28 | — | — | EP | claimed |
| US-4307107-A | Arthropodicidal N,N-dimethyl-O-(1,3,4-substituted-pyrazol(5)yl)-carbamic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |