Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241760 | 0.99 | PSMB1 (0.50) | PSMB1PSMB5LTA4HPTGS2HRH3 | |
| Hydrochloric Acid SCHEMBL11232363 | 0.99 | ALDH1A1 (0.47) | PSMB1PSMB5LTA4HPTGS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11249166 | 0.97 | PSMB1 (0.49) | PSMB1PSMB5LTA4HPTGS2ALDH1A1 | |
| SCHEMBL11245857 | 0.88 | ALDH1A1 (0.52) | ALDH1A1HTR1AKCNH2TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL11243365 | 0.87 | ALDH1A1 (0.51) | ALDH1A1HTR1AKCNH2TSHRMEN1 | |
| SCHEMBL11328261 | 0.77 | KDM2B (0.50) | PSMB1PSMB5ALDH1A1HRH3MEN1 | |
| SCHEMBL11324542 | 0.76 | KDM2B (0.49) | PSMB1PSMB5ALDH1A1HRH3MEN1 | |
| SCHEMBL14277939 | 0.74 | ESR1 (0.53) | ALDH1A1SLC6A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6979432 | 0.73 | L3MBTL1 (0.51) | PSMB1PSMB5LTA4HALDH1A1NPC1 | |
| SCHEMBL6100704 | 0.73 | L3MBTL1 (0.51) | PSMB1PSMB5LTA4HALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342763-A | USEFUL AS ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTITUSSIVE AGENTS | PROVESAN S.A. (CH) | 1982-08-03 | — | — | US | claimed |