SCHEMBL11242965

SCHEMBL11242965

O=CNNc1cccc(NC(=S)Nc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.56
ALDH1A1 P00352 6/20 0.55
CYP3A4 P08684 2/20 0.55
TAS2R38 P59533 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MEN1 O00255 4/20 0.54
KDM4E B2RXH2 1/20 0.54
KDR P35968 1/20 0.51
MAPT P10636 4/20 0.50
GAA P10253 4/20 0.47
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
LMNA P02545 1/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
NOX1 Q9Y5S8 1/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11051368 0.90 SIRT1 (0.50) KMT2AALDH1A1CYP3A4TAS2R38HSD17B10
SCHEMBL9174022 0.88 ALDH1A1 (0.61) KMT2AALDH1A1CYP3A4TAS2R38HSD17B10
SCHEMBL10904255 0.85 SIRT1 (0.58) KMT2AHSD17B10MEN1KDRMAPT
SCHEMBL11684135 0.84 CYP1A2 (0.60) KMT2AALDH1A1MEN1KDM4EMAPT
SCHEMBL6537234 0.83 KMT2A (0.54) KMT2AALDH1A1MEN1KDRMAPT
SCHEMBL7767586 0.81 ALDH1A1 (0.50) KMT2AALDH1A1CYP3A4TAS2R38HSD17B10
SCHEMBL11686177 0.81 ALDH1A1 (0.55) KMT2AALDH1A1CYP3A4TAS2R38HSD17B10
SCHEMBL11309583 0.81 GAA (0.60) KMT2AALDH1A1CYP3A4TAS2R38HSD17B10
SCHEMBL9785826 0.79 ALDH1A1 (0.58) KMT2AALDH1A1CYP3A4TAS2R38HSD17B10
SCHEMBL11335238 0.78 MEN1 (0.52) KMT2AALDH1A1MEN1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4031127-A Acyl hydrazino thiourea derivatives as photographic nucleating agents EASTMAN KODAK COMPANY (US) 1977-06-21 US claimed
US-4358528-A Formation of black-and-white silver-containing negative images by a diffusion transfer process FUJI PHOTO FILM CO., LTD. (JP) 1982-11-09 US disclosed
US-4309499-A PROCESSING WITH ONE SOLUTION CONTAINING FOGGING AGENT, FOG PROMOTER, DEVELOPER, AND SOLVENT FOR SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1982-01-05 US disclosed
US-4030925-A Photographic compositions and elements including internal latent image silver halide grains and acylhydrazinophenylthiourea nucleating agents therefor EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed