Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244892 | 0.87 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1HMOX2TBXAS1 | |
| SCHEMBL11229525 | 0.87 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL11237322 | 0.86 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1HMOX2 | |
| SCHEMBL11248755 | 0.83 | CYP19A1 (0.57) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11248355 | 0.83 | CYP19A1 (0.59) | CYP11B1CYP11B2CYP19A1HMOX2TBXAS1 | |
| SCHEMBL11238973 | 0.83 | HMOX2 (0.64) | CYP11B1CYP11B2CYP19A1HMOX2TBXAS1 | |
| SCHEMBL11240992 | 0.78 | HMOX2 (0.46) | CYP11B1CYP11B2CYP19A1HMOX2TBXAS1 | |
| SCHEMBL12205 | 0.78 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL5523502 | 0.78 | ALPG (0.62) | CYP11B1CYP11B2CYP19A1 | |
| Sulfuric Acid SCHEMBL11263269 | 0.78 | HMOX2 (0.58) | CYP11B1CYP11B2CYP19A1HMOX2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |