Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 1.00 |
| ▸ | CYP11B2 | P19099 | 11/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.65 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | QPCT | Q16769 | 1/20 | 0.64 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.64 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394308 | 0.88 | CYP11B1 (0.83) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL6987181 | 0.84 | CYP11B1 (0.72) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL12299569 | 0.83 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL14647046 | 0.83 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL15872000 | 0.82 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL24733003 | 0.80 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL10997898 | 0.80 | CYP11B1 (0.71) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL1848631 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL9747422 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 | |
| SCHEMBL860653 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2ADRA2CCYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62187403-A | — | — | None | — | — | JP | disclosed |
| EP-3152210-B1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023274257-A1 | IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF | 诸葛国琴 | 2023-01-05 | — | — | WO | disclosed |
| US-20200109139-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2020-04-09 | — | — | US | disclosed |
| US-20170029418-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2017-02-02 | — | — | US | disclosed |
| US-20170029418-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2017-02-02 | — | — | US | disclosed |
| EP-2499146-B1 | TRICYCLIC PYRAZOL AMINE DERIVATIVES | MERCK SERONO SA (CH) | 2016-09-21 | — | — | EP | disclosed |
| US-20150344473-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-9150519-B2 | 6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis | MERCK SERONO SA (CH) | 2015-10-06 | — | — | US | disclosed |
| US-20150183812-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2015-07-02 | — | — | US | disclosed |
| US-7378423-B2 | Antiproliferative, anticancer, antitumor agents; rheumatism; N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]-phenyl}-acetamide; a p15, and/or a protein inducing action, and/or an MEK inhibitory action; side effect reduction | JAPAN TOBACCO INC. (JP) | 2008-05-27 | — | — | US | disclosed |
| US-20080027060-A1 | DIPEPTIDE NITRILES | ALTMANN EVA | 2008-01-31 | — | — | US | disclosed |
| US-20080027060-A1 | DIPEPTIDE NITRILES | ALTMANN EVA | 2008-01-31 | — | — | US | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| US-5100890-A | Antidepressants, Fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0218118-B1 | ARYLMETHYL AZOLES AND THEIR SALTS, METHOD FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-5023357-A | Arylmethylazole preparation processes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |
| US-4876354-A | FUNGICIDES, ANTIDEPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| JP-S62187403-A | PLANT-GROWTH REGULATOR | RIKAGAKU KENKYUSHO | 1987-08-15 | — | — | JP | disclosed |
| EP-0218118-A1 | Arylmethyl azoles and their salts, method for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344473-A1 | TANK-BINDING KINASE INHIBITOR COMPOUNDS | TBKBP1, TNKS1BP1, TNKS | CYP11B1 4237/4885CYP11B2 4441/4885ADRA2C 4736/4885 |
| US-20170029418-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | TYMP, TYMS, DPYD | CYP11B1 825/4885CYP11B2 1073/4885ADRA2C 4545/4885 |
| US-20200109139-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | TYMP, TYMS, DPYD | CYP11B1 825/4885CYP11B2 1073/4885ADRA2C 4545/4885 |
| US-20150183812-A1 | PYRIMIDINE COMPOUND AND MEDICAL USE THEREOF | TYMP, TYMS, DPYD | CYP11B1 825/4885CYP11B2 1073/4885ADRA2C 4545/4885 |
| US-20080027060-A1 | DIPEPTIDE NITRILES | CTSL, CTSS, CTSB | CYP11B1 2487/4885CYP11B2 3447/4885ADRA2C 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.