Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX2 | P30519 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245721 | 0.87 | POLB (0.48) | CYP11B1CYP11B2TDP1POLBCTDSP1 | |
| SCHEMBL11247258 | 0.87 | TBXAS1 (0.44) | HMOX2CYP11B1CYP11B2TDP1POLB | |
| SCHEMBL11256237 | 0.86 | TBXAS1 (0.43) | HMOX2CYP11B1CYP11B2TDP1POLB | |
| SCHEMBL11261839 | 0.85 | KDM4E (0.50) | TDP1POLBCTDSP1ALDH1A1TBXAS1 | |
| SCHEMBL11245838 | 0.82 | CYP11B1 (0.60) | HMOX2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL11248355 | 0.80 | CYP19A1 (0.59) | HMOX2CYP11B1CYP11B2ALDH1A1CYP19A1 | |
| SCHEMBL11243136 | 0.78 | CYP11B1 (0.63) | HMOX2CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL11269463 | 0.78 | POLB (0.47) | CYP11B1CYP11B2TDP1POLBCTDSP1 | |
| SCHEMBL11237322 | 0.77 | CYP11B1 (0.59) | HMOX2CYP11B1CYP11B2ALDH1A1CYP19A1 | |
| SCHEMBL11238564 | 0.76 | ALDH1A1 (0.47) | HMOX2CYP11B1CYP11B2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |