Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11243669 | 0.99 | LMNA (0.42) | LMNAMAPTNFKB1NFKB2RELA | |
| SCHEMBL11231986 | 0.91 | CES2 (0.35) | LMNAALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL11248129 | 0.90 | CES2 (0.34) | LMNAALDH1A1HTT | |
| SCHEMBL11244408 | 0.83 | CHRM2 (0.35) | HTT | |
| Hydrochloric Acid SCHEMBL11236146 | 0.82 | CHRM2 (0.34) | HTT | |
| Hydrochloric Acid SCHEMBL11234187 | 0.82 | CHRM2 (0.34) | HTT | |
| Hydrochloric Acid SCHEMBL11241242 | 0.82 | CHRM2 (0.34) | HTT | |
| Hydrochloric Acid SCHEMBL11247205 | 0.80 | RAB9A (0.36) | NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11248592 | 0.78 | CCNE1 (0.39) | HRH2HRH1TRPV1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL11247887 | 0.75 | EGFR (0.39) | LMNAMAPTNPC1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320127-A | Pyrido[3,2-e]-as-triazines | EDYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-03-16 | — | — | US | claimed |
| US-4320127-A | Pyrido[3,2-e]-as-triazines | EDYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-03-16 | — | — | US | disclosed |