Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | AGER | Q15109 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881360 | 0.91 | CNR2 (0.59) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL11234141 | 0.88 | CNR2 (0.57) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL7361369 | 0.85 | KDM4E (0.56) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL11229411 | 0.85 | MAPT (0.51) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL7367595 | 0.84 | KDM4E (0.67) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL6987666 | 0.83 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL296670 | 0.82 | KDM4E (0.69) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL11239278 | 0.81 | CNR2 (0.58) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| Hydrochloric Acid SCHEMBL7853761 | 0.81 | KDM4E (0.67) | MAPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL7364079 | 0.80 | KDM4E (0.61) | MAPTALDH1A1KDM4ENPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |