Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 2/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236348 | 0.92 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2QPCTTBXAS1 | |
| SCHEMBL11228695 | 0.86 | CYP1A2 (0.55) | CYP19A1CYP11B1CYP11B2TBXAS1ALDH1A1 | |
| SCHEMBL11243099 | 0.86 | TBXAS1 (0.59) | CYP19A1CYP11B1CYP11B2QPCTTBXAS1 | |
| SCHEMBL11265550 | 0.86 | TBXAS1 (0.57) | CYP19A1TBXAS1 | |
| SCHEMBL11238134 | 0.86 | MEN1 (0.59) | CYP19A1QPCTTBXAS1ALDH1A1KDM4E | |
| SCHEMBL11261566 | 0.84 | KDM4E (0.63) | QPCTTBXAS1ALDH1A1KDM4E | |
| SCHEMBL6948570 | 0.83 | NOS1 (0.56) | CYP19A1QPCTTBXAS1 | |
| SCHEMBL11248355 | 0.83 | CYP19A1 (0.59) | CYP19A1CYP11B1CYP11B2TBXAS1ALDH1A1 | |
| SCHEMBL11261839 | 0.82 | KDM4E (0.50) | QPCTTBXAS1ALDH1A1KDM4E | |
| SCHEMBL11259784 | 0.81 | TBXAS1 (0.55) | QPCTTBXAS1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |