Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936623 | 0.85 | IDO1 (0.60) | IDO1TAAR1ALDH1A1GAAMAPT | |
| SCHEMBL14655700 | 0.77 | KMT2A (0.64) | IDO1TAAR1KMT2A | |
| SCHEMBL266563 | 0.77 | KMT2A (0.64) | IDO1TAAR1KMT2A | |
| SCHEMBL30249073 | 0.77 | KMT2A (0.64) | IDO1TAAR1KMT2A | |
| SCHEMBL11236282 | 0.76 | IDO1 (0.55) | IDO1TAAR1ALDH1A1GAAMAPT | |
| SCHEMBL11230270 | 0.76 | IDO1 (0.55) | IDO1TAAR1ALDH1A1GAAMAPT | |
| SCHEMBL1520836 | 0.76 | IDO1 (1.00) | IDO1TAAR1ALDH1A1GAAMAPT | |
| SCHEMBL26654 | 0.76 | IDO1 (0.69) | IDO1TAAR1ALDH1A1GAAMAPT | |
| SCHEMBL31290863 | 0.76 | IDO1 (0.69) | IDO1TAAR1ALDH1A1GAAMAPT | |
| SCHEMBL10607688 | 0.76 | IDO1 (0.69) | IDO1TAAR1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322342-A | Analgesic compounds | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| US-4259234-A | OLIGOPEPTIDES FOR PARENTERAL ADMINISTRATION | ELI LILLY AND COMPANY (US) | 1981-03-31 | — | — | US | disclosed |