Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222740 | 0.83 | L3MBTL1 (0.49) | ALDH1A1GAAMAPTATML3MBTL1 | |
| SCHEMBL11230270 | 0.82 | IDO1 (0.55) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL12936623 | 0.79 | IDO1 (0.60) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL11243877 | 0.76 | IDO1 (0.61) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL31290863 | 0.74 | IDO1 (0.69) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL26654 | 0.74 | IDO1 (0.69) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL29377714 | 0.74 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL17804 | 0.74 | IDO1 (0.57) | IDO1TAAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL10607688 | 0.74 | IDO1 (0.69) | IDO1TAAR1ABCB1CHRM2CHRM1 | |
| SCHEMBL31048 | 0.74 | IDO1 (0.69) | IDO1TAAR1ABCB1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |