Butyric Acid

Butyric Acid

SCHEMBL11243928

CCCC(=O)O.NC1(N)C=CC(C(=O)c2ccccc2)=CC1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
HPGD P15428 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.34
CNR2 P34972 1/20 0.34
NR4A2 P43354 1/20 0.34
ALDH1A1 P00352 6/20 0.34
KMT2A Q03164 2/20 0.34
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
GLA P06280 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528382 0.88 ALDH1A1 (0.42) HPGDL3MBTL1SMN1; SMN2POLBALDH1A1
Benzophenone SCHEMBL28991975 0.86 ALDH1A1 (0.45) HPGDL3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL28271865 0.76 ALDH1A1 (0.39) HPGDL3MBTL1POLBALDH1A1RAB9A
Hydrochloric Acid SCHEMBL8844133 0.75 ALDH1A1 (0.38) HPGDL3MBTL1POLBALDH1A1RAB9A
SCHEMBL27698253 0.75 CES2 (0.39) CES2CES1CNR2ALDH1A1
SCHEMBL28159138 0.75 CES2 (0.45) CES2CES1HPGDL3MBTL1SMN1; SMN2
SCHEMBL27557280 0.75 ALDH1A1 (0.41) HPGDL3MBTL1SMN1; SMN2POLBALDH1A1
Hexane SCHEMBL27462417 0.75 CES2 (0.41) CES2CES1HPGDCNR2ALDH1A1
SCHEMBL27823388 0.74 RAB9A (0.39) HPGDL3MBTL1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL27954434 0.74 MAPK1 (0.38) CES2CES1HPGDL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4340711-A Process for the preparation of granular silarylenesiloxane copolymers polymerized under conditions of shear GENERAL ELECTRIC COMPANY (US) 1982-07-20 US disclosed