SCHEMBL11244271

SCHEMBL11244271

CCCC(=O)OC(=O)C(C)=O

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
CES1 P23141 2/20 0.39
CES2 O00748 1/20 0.39
HDAC3 O15379 4/20 0.38
HDAC1 Q13547 4/20 0.38
HDAC2 Q92769 4/20 0.38
HDAC8 Q9BY41 4/20 0.38
FFAR3 O14843 3/20 0.38
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.36
HDAC6 Q9UBN7 1/20 0.33
LMNA P02545 1/20 0.32
NAAA Q02083 1/20 0.32
DGKA P23743 1/20 0.32
GLO1 Q04760 1/20 0.32
CTSD P07339 1/20 0.32
BCL9 O00512 1/20 0.32
CTNNB1 P35222 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28541873 0.98 ALDH1A1 (0.64) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL6426591 0.87 ALDH1A1 (0.46) ALDH1A1CES1TDP1TSHRLMNA
SCHEMBL28743098 0.84 DGKA (0.52) ALDH1A1CES1CES2TDP1TSHR
SCHEMBL9276995 0.82 DGKA (0.55) ALDH1A1CES1CES2TDP1TSHR
SCHEMBL777608 0.81 ALDH1A1 (0.42) ALDH1A1CES1FFAR3TDP1TSHR
SCHEMBL766145 0.81 ALDH1A1 (0.61) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL30568759 0.81 ALDH1A1 (1.00) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL8158 0.81 ALDH1A1 (1.00) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL19810344 0.80 ALDH1A1 (0.67) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL6934724 0.80 ALDH1A1 (0.67) ALDH1A1CES1CES2HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11688519-B2 Method and system for monitoring the gut health of an individual TATA CONSULTANCY SERVICES LIMITED (IN) 2023-06-27 US disclosed
US-4317843-A PSEUDOMONAS AS FOOD IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-03-02 US disclosed