Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CES2 | O00748 | 6/20 | 0.46 |
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19810344 | 0.90 | ALDH1A1 (0.67) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL28947326 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL7530726 | 0.82 | CES2 (0.55) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL8158 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL30568759 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL27448436 | 0.80 | CES2 (0.52) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL11244271 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL27419423 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL17477083 | 0.78 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL9556715 | 0.78 | ALDH1A1 (0.94) | ALDH1A1CES2CES1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5736129-A | Flow cytometric pharmacosensitivity assay and method of cancer treatment | SHAKER CORPORATION, A DELAWARE CORPORATION | 1998-04-07 | — | — | US | disclosed |
| WO-1997019189-A1 | FLOW CYTOMETRIC PHARMACOSENSITIVITY ASSAY AND METHOD OF CANCER TREATMENT | MEDENICA RAJKO D (US) | 1997-05-29 | — | — | WO | disclosed |