SCHEMBL11244353

SCHEMBL11244353

Cc1ccc(N=O)cc1.Cc1ccc(N=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HSD17B10 Q99714 3/20 0.52
MAPK1 P28482 2/20 0.52
TSHR P16473 2/20 0.52
TP53 P04637 1/20 0.52
HIF1A Q16665 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
ACHE P22303 2/20 0.50
KMT2A Q03164 1/20 0.50
HTR3E A5X5Y0 2/20 0.46
HTR3B O95264 2/20 0.46
HTR3A P46098 2/20 0.46
HTR3D Q70Z44 2/20 0.46
HTR3C Q8WXA8 2/20 0.46
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
PLAU P00749 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL941642 1.00
SCHEMBL13547631 0.92 ALDH1A1 (0.46) ALDH1A1HSD17B10MAPK1TSHRTP53
SCHEMBL13100599 0.85 NFE2L2 (0.52) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL27251886 0.85 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPK1TSHRTP53
SCHEMBL27251896 0.85 TSHR (0.48) ALDH1A1HSD17B10MAPK1TSHRTP53
SCHEMBL9225008 0.85 ALDH1A1 (0.65) ALDH1A1HSD17B10MAPK1TSHRTP53
SCHEMBL27251885 0.85 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPK1TSHRTP53
SCHEMBL27251890 0.85 ALDH1A1 (0.54) ALDH1A1HSD17B10MAPK1TSHRTP53
SCHEMBL22593741 0.83 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPK1TSHRTP53
SCHEMBL22931465 0.83 TSHR (0.46) ALDH1A1HSD17B10MAPK1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-4340624-A STYRYL-LIKE COMPOUNDS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-07-20 US disclosed
US-4003633-A Color display device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-01-18 US disclosed