Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | FGF23 | Q9GZV9 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941642 | 0.85 | — | — | |
| SCHEMBL11244353 | 0.85 | ALDH1A1 (0.52) | PTGS2PTGS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28162394 | 0.83 | ALDH1A1 (0.65) | PTGS2PTGS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18427609 | 0.82 | RAB9A (0.57) | NFE2L2PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16547155 | 0.81 | NFE2L2 (0.56) | NFE2L2PTGS2PTGS1NPC1RAB9A | |
| SCHEMBL318786 | 0.80 | NFE2L2 (0.74) | NFE2L2PTGS2PTGS1NPC1RAB9A | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 0.80 | NFE2L2 (0.74) | NFE2L2PTGS2PTGS1NPC1RAB9A | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1793692 | 0.80 | NFE2L2 (0.74) | NFE2L2PTGS2PTGS1NPC1RAB9A | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305580 | 0.80 | NFE2L2 (0.74) | NFE2L2PTGS2PTGS1NPC1RAB9A | |
| SCHEMBL318785 | 0.80 | NFE2L2 (0.74) | NFE2L2PTGS2PTGS1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100266500-A1 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266500-A1 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | APP, APBA1, PSEN1 | NFE2L2 2543/4885PTGS2 3442/4885PTGS1 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.