Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.57 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.57 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042261 | 0.98 | PLAAT3 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| SCHEMBL11037985 | 0.97 | PLAAT3 (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| SCHEMBL1239196 | 0.93 | ALOX5 (0.64) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| SCHEMBL28141430 | 0.86 | F2RL1 (0.66) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| SCHEMBL1171967 | 0.85 | LTB4R (0.67) | ALOX5F2RL1CALM1LTB4RFFAR1 | |
| SCHEMBL11244441 | 0.84 | ALOX5 (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| SCHEMBL9484086 | 0.83 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4RFFAR1 | |
| SCHEMBL9663959 | 0.83 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4RFFAR1 | |
| SCHEMBL8001859 | 0.83 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4RFFAR1 | |
| SCHEMBL709381 | 0.83 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4RFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334089-A | HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |