Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374754 | 0.90 | KMT2A (0.38) | GHSRKMT2AMEN1GAARAB9A | |
| SCHEMBL11241792 | 0.88 | CNR2 (0.41) | CNR2GHSRGPR88CHRM5EDNRB | |
| SCHEMBL11239691 | 0.83 | ALDH1A1 (0.38) | GHSRKMT2AMEN1GAARAB9A | |
| SCHEMBL11244555 | 0.80 | CNR2 (0.36) | CNR2FFAR4GHSRGPR88EGLN1 | |
| SCHEMBL11248616 | 0.79 | ALDH1A1 (0.40) | KMT2AMEN1RAB9ANPY5RTP53 | |
| SCHEMBL11235691 | 0.77 | CNR2 (0.36) | CNR2FFAR4GPR88EGLN1KMT2A | |
| SCHEMBL11244078 | 0.77 | MEN1 (0.36) | CNR2GHSRKMT2AMEN1GAA | |
| SCHEMBL11382459 | 0.77 | CNR2 (0.39) | CNR2CHRM5KMT2AMEN1TP53 | |
| SCHEMBL11240578 | 0.76 | CYP3A4 (0.36) | FFAR4KMT2AMEN1RAB9ANPY5R | |
| SCHEMBL11365552 | 0.74 | ATM (0.42) | CHRM5KMT2AMEN1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |