Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | APP | P05067 | 6/20 | 0.39 |
| ▸ | SNCA | P37840 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239691 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TDP1CYP3A4HPGDHIF1A | |
| SCHEMBL11374754 | 0.87 | KMT2A (0.38) | ALDH1A1TDP1HPGDMAPTMEN1 | |
| SCHEMBL11237226 | 0.83 | TRPV1 (0.36) | ALDH1A1TDP1CYP3A4HPGDHIF1A | |
| SCHEMBL11377272 | 0.81 | TDP1 (0.48) | ALDH1A1TDP1CYP3A4HPGDHIF1A | |
| SCHEMBL11441974 | 0.81 | TDP1 (0.48) | ALDH1A1TDP1CYP3A4HPGDHIF1A | |
| SCHEMBL11235932 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TDP1CYP3A4HPGDHIF1A | |
| SCHEMBL7197746 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4HPGDHIF1A | |
| SCHEMBL11244546 | 0.79 | CNR2 (0.41) | MAPTMEN1KMT2ANPY5RRAB9A | |
| SCHEMBL11232126 | 0.78 | KDM4E (0.37) | ALDH1A1TDP1CYP3A4HPGDMAPT | |
| SCHEMBL11370697 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | claimed |
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |