Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.44 |
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | HTR1A | P08908 | 7/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10894830 | 0.99 | DRD2 (0.44) | DRD2HTR2AHTR1AHTR7POLB | |
| SCHEMBL11247050 | 0.89 | HTR2A (0.46) | HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL10893944 | 0.88 | HTR2A (0.45) | HTR2AHTR7 | |
| SCHEMBL11283504 | 0.87 | DRD2 (0.44) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL10940365 | 0.86 | HTR2A (0.41) | DRD2HTR2AHTR1A | |
| SCHEMBL10897685 | 0.78 | DRD2 (0.43) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL11244560 | 0.78 | HTR1A (0.55) | DRD2HTR2AHTR1A | |
| SCHEMBL10893799 | 0.77 | HTR2A (0.41) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL11163883 | 0.77 | HTR2A (0.46) | HTR2AHTR7 | |
| SCHEMBL10898277 | 0.77 | HTR2A (0.46) | DRD2HTR2AHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | claimed |