Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.55 |
| ▸ | DRD2 | P14416 | 10/20 | 0.55 |
| ▸ | HTR2A | P28223 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10894851 | 0.99 | HTR1A (0.54) | HTR1ADRD2HTR2A | |
| SCHEMBL10895899 | 0.94 | P2RX7 (0.57) | HTR1ADRD2HTR2A | |
| SCHEMBL11247057 | 0.88 | HTR2A (0.53) | HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL10893966 | 0.88 | HTR2A (0.52) | HTR1ADRD2HTR2A | |
| SCHEMBL11163898 | 0.83 | USP2 (0.61) | HTR1ADRD2HTR2A | |
| SCHEMBL10893812 | 0.83 | USP2 (0.54) | HTR1ADRD2HTR2A | |
| SCHEMBL10896910 | 0.83 | DRD2 (0.61) | DRD2HTR2A | |
| SCHEMBL10897702 | 0.83 | HTR1A (0.51) | HTR1ADRD2HTR2A | |
| SCHEMBL10898282 | 0.83 | P2RX7 (0.52) | HTR1ADRD2HTR2A | |
| Bromide SCHEMBL10898200 | 0.82 | USP2 (0.60) | HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352811-A | NEUROLEPTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-10-05 | — | — | US | claimed |