Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249758 | 0.90 | RXFP1 (0.51) | RXFP1FFAR1FFAR4ABCB1ABCG2 | |
| SCHEMBL11244569 | 0.81 | FFAR1 (0.76) | RXFP1FFAR1FFAR4KDM4EMEN1 | |
| SCHEMBL30645136 | 0.81 | FFAR4 (0.54) | FFAR1FFAR4KDM4EMEN1KMT2A | |
| SCHEMBL365306 | 0.81 | FFAR4 (0.54) | FFAR1FFAR4KDM4EMEN1KMT2A | |
| SCHEMBL11251408 | 0.78 | CA12 (0.49) | ABCB1ABCG2KDM4EMEN1KMT2A | |
| SCHEMBL15682777 | 0.76 | NPC1 (0.59) | MEN1KMT2AALDH1A1TDP1MAPK14 | |
| SCHEMBL11252360 | 0.76 | MAPT (0.47) | FFAR1ABCB1ABCG2MEN1KMT2A | |
| SCHEMBL13019460 | 0.75 | ALDH1A1 (0.61) | RXFP1KDM4EKMT2AALDH1A1HTT | |
| SCHEMBL18047219 | 0.74 | RXFP1 (0.53) | RXFP1FFAR1FFAR4KDM4EMEN1 | |
| SCHEMBL18047218 | 0.74 | RXFP1 (0.53) | RXFP1FFAR1FFAR4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |