Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | KMO | O15229 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 4/20 | 0.56 |
| ▸ | CPA3 | P15088 | 2/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347491 | 0.94 | KMO (0.63) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL3664996 | 0.94 | KMO (0.63) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL2338269 | 0.94 | KMO (0.63) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL7315538 | 0.89 | TSHR (0.75) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL3104186 | 0.89 | TSHR (0.75) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL11252444 | 0.84 | TSHR (0.64) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL11127553 | 0.84 | BCL2L1 (0.64) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL6675156 | 0.84 | NPC1 (0.53) | TSHRKMOCPA1CPA3CPB1 | |
| SCHEMBL28181738 | 0.83 | CYP1A2 (0.77) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL3110072 | 0.83 | LDHA (0.54) | KMOBCL2L1MCL1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329495-A | USEFUL AS ANALGESICS OR ANTICONVULSANTS, CHIRAL 2-(2-BENZYL-3-MERCAPTOPROPIONYLAMINO)-THIOBUTYRIC ACIDS, OR ALKANOL DERIVATIVES | PFIZER INC. (US) | 1982-05-11 | — | — | US | disclosed |