Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245297 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AGFERFFAR1NPC1 | |
| SCHEMBL18669064 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AGFERPOLBHDAC3 | |
| SCHEMBL6690806 | 0.83 | RAB9A (0.67) | SMN1; SMN2RAB9AGFERFFAR1NPC1 | |
| SCHEMBL6777623 | 0.83 | CA12 (0.63) | RAB9AGAAMAPTCA1HIF1A | |
| SCHEMBL7662583 | 0.80 | ALDH1A1 (0.67) | SMN1; SMN2RAB9ANPC1HDAC1GAA | |
| SCHEMBL11244675 | 0.79 | MAPT (0.58) | SMN1; SMN2RAB9AGFERFFAR1NPC1 | |
| SCHEMBL11511314 | 0.78 | MEN1 (0.68) | SMN1; SMN2RAB9AGFERFFAR1POLB | |
| SCHEMBL7988500 | 0.77 | RAB9A (0.65) | SMN1; SMN2RAB9AGFERFFAR1NPC1 | |
| SCHEMBL27549523 | 0.77 | PARP10 (0.52) | SMN1; SMN2RAB9AGFERFFAR1MAPT | |
| SCHEMBL14018652 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9AGFERFFAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |