Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351076 | 0.85 | TDP1 (0.39) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11275809 | 0.79 | ALDH1A1 (0.47) | L3MBTL1KCNH2KDM4EALDH1A1HSD17B14 | |
| SCHEMBL9789537 | 0.79 | TDP1 (0.35) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11245639 | 0.78 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10933144 | 0.78 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11245643 | 0.78 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL13062898 | 0.77 | TDP1 (0.61) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11456425 | 0.76 | TDP1 (0.39) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10706094 | 0.74 | TDP1 (0.53) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10706088 | 0.74 | TDP1 (0.53) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323574-A | INSECTICIDES, PESTICIDES | ZOECON CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |