Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351076 | 0.88 | TDP1 (0.39) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11244705 | 0.79 | TDP1 (0.38) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9789540 | 0.76 | ALDH1A1 (0.40) | TDP1HSD17B14ALDH1A1 | |
| SCHEMBL11275809 | 0.75 | ALDH1A1 (0.47) | L3MBTL1HSD17B14KCNH2PLA2G10PPARG | |
| SCHEMBL10933144 | 0.74 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11245643 | 0.74 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11245639 | 0.74 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10706101 | 0.72 | TDP1 (0.53) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10706088 | 0.72 | TDP1 (0.53) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10706094 | 0.72 | TDP1 (0.53) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049585-A | Certain 3,3-bis-(difluoro methyl)2,2-dimethyl-cyclopropane carboxylates having insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |