SCHEMBL11275809

SCHEMBL11275809

CC(=O)OCc1cccc(Oc2ccccc2)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
KCNH2 Q12809 1/20 0.44
HSD17B14 Q9BPX1 1/20 0.42
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
OPRM1 P35372 1/20 0.39
F2 P00734 2/20 0.39
F10 P00742 2/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
ST14 Q9Y5Y6 1/20 0.39
PPARG P37231 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
PDE5A O76074 1/20 0.37
PLA2G10 O15496 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11368795 0.82 P2RX3 (0.41) KCNH2HSD17B14OPRM1F2F10
SCHEMBL11062094 0.81 KCNH2 (0.38) ALDH1A1KCNH2HSD17B14OPRM1F2
SCHEMBL11351076 0.81 TDP1 (0.39) ALDH1A1KCNH2HSD17B14F2F10
SCHEMBL7839773 0.81 ALDH1A1 (0.58) ALDH1A1
SCHEMBL11244705 0.79 TDP1 (0.38) ALDH1A1KCNH2HSD17B14OPRM1PPARG
SCHEMBL11071446 0.79 ALDH1A1 (0.38) ALDH1A1KCNH2HSD17B14
SCHEMBL27690318 0.79 KCNH2 (0.53) ALDH1A1KCNH2HSD17B14CYP1A2CYP2C19
SCHEMBL10871695 0.79 FFAR1 (0.53) HSD17B14OPRM1F2F10PRSS1
SCHEMBL11065707 0.79 ADAMTS4 (0.39) ALDH1A1KDM4ERAB9AL3MBTL1
SCHEMBL11066972 0.78 ALDH1A1 (0.36) ALDH1A1KCNH2HSD17B14PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55092370-A None JP disclosed
US-4338326-A PESTICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed
US-4251662-A INSECTICIDES, MITICIDES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1981-02-17 US disclosed
US-4223033-A Substituted pyridine methyl esters of naphthyl acids ZOECON CORPORATION (US) 1980-09-16 US disclosed
JP-S5592370-A PHENOXYPYRIDINE DERIVATIVE AND ITS PREPARATION NISSAN CHEM IND LTD 1980-07-12 JP disclosed