Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263763 | 0.89 | TDP1 (0.37) | TYRATMTDP1CYP1A2CYP3A4 | |
| SCHEMBL11261908 | 0.79 | CYP1A2 (0.37) | TYRCYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL9577447 | 0.77 | TYR (0.40) | TYRTDP1KDM4EALDH1A1MAPT | |
| SCHEMBL11400960 | 0.77 | TYR (0.42) | TYRCYP2C9KDM4EALDH1A1MAPT | |
| SCHEMBL11252515 | 0.77 | CYP2C19 (0.35) | TYRATMTDP1CYP1A2CYP3A4 | |
| SCHEMBL11254545 | 0.77 | ALDH1A1 (0.45) | ATMTDP1CYP1A2TSHRCYP2C19 | |
| SCHEMBL10413283 | 0.74 | TYR (0.38) | TYRTDP1KDM4E | |
| SCHEMBL11249531 | 0.74 | GAA (0.33) | GAAMAPTTP53 | |
| SCHEMBL9491543 | 0.72 | TDP1 (0.43) | ATMTDP1CYP1A2TSHRCYP2C19 | |
| SCHEMBL10413285 | 0.72 | TYR (0.36) | TYRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346025-A | Stabilized vinyl chloride polymer comprising a phenylethylidene aryl phosphite | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |