SCHEMBL9577447

SCHEMBL9577447

CC(c1ccccc1)c1ccc(OP(Oc2ccc(C(C)c3ccccc3)cc2C(C)c2ccccc2)Oc2ccc(C(C)c3ccccc3)cc2C(C)c2ccccc2)c(C(C)c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.40
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
DAO P14920 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
LMNA P02545 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CASR P41180 2/20 0.32
ESR1 P03372 1/20 0.31
PDCD1 Q15116 1/20 0.31
ESR2 Q92731 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
SCN4A P35499 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10413285 0.91 TYR (0.36) TYRTDP1L3MBTL1CASR
SCHEMBL10413283 0.87 TYR (0.38) TYRTDP1L3MBTL1DAOADRA2A
SCHEMBL4900277 0.82 TYR (0.41) TYRL3MBTL1DAOADRA2AADRA2C
SCHEMBL11244840 0.77 TYR (0.34) TYRTDP1KDM4EALDH1A1MAPT
SCHEMBL15501165 0.76 CALM1 (0.39) TYRL3MBTL1KDM4EALDH1A1MAPT
SCHEMBL14408937 0.75 ALDH1A1 (0.40) TYRL3MBTL1LMNAKDM4EALDH1A1
SCHEMBL10903559 0.75 GPR84 (0.40) TYR
SCHEMBL3989420 0.74 ESR1 (0.38) TYRADRA2AADRA2CESR1PDCD1
SCHEMBL11344581 0.74 TYR (0.38) TYR
SCHEMBL10413327 0.73 TYR (0.37) TYRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254348-B1 PROCESS OF (CO)POLYMERIZATION OF ALPHA-OLEFINS IN THE PRESENCE OF ANTIOXIDANTS ENICHEM SYNTHESIS S.p.A. (IT) 1993-08-25 EP claimed
US-4824885-A PHOSPHITES OR PHOSPHONITES ENICHEM SINTESI S.P.A. (IT) 1989-04-25 US claimed
EP-0254348-A2 Process of (co)polymerization of alpha-olefins in the presence of antioxidants ENICHEM SYNTHESIS S.p.A. (IT) 1988-01-27 EP claimed
EP-0254348-B1 PROCESS OF (CO)POLYMERIZATION OF ALPHA-OLEFINS IN THE PRESENCE OF ANTIOXIDANTS ENICHEM SYNTHESIS S.p.A. (IT) 1993-08-25 EP disclosed
US-4824885-A PHOSPHITES OR PHOSPHONITES ENICHEM SINTESI S.P.A. (IT) 1989-04-25 US disclosed
EP-0254348-A2 Process of (co)polymerization of alpha-olefins in the presence of antioxidants ENICHEM SYNTHESIS S.p.A. (IT) 1988-01-27 EP disclosed