Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568266 | 0.77 | GAA (0.46) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL28000167 | 0.74 | GAA (0.43) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL2154632 | 0.73 | GAA (0.50) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL11244866 | 0.72 | ALDH1A1 (0.49) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL28866136 | 0.72 | GAA (0.49) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL11244858 | 0.71 | POLB (0.41) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL11748737 | 0.70 | ALDH1A1 (0.54) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL103547 | 0.70 | GAA (0.46) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL28020967 | 0.70 | ALDH1A1 (0.49) | GAAPOLBHTR1AADRA2AADRA2B | |
| SCHEMBL1942660 | 0.69 | ALDH1A1 (0.53) | GAAPOLBHTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348401-A | ANTIHISTAMINIC, ANTIEDEMIC, ANTIPHLOGISTIC | BOEHRINGER MANNHEIM GMBH (DE) | 1982-09-07 | — | — | US | disclosed |